I played a bit with the Dune version, and here are my thoughts.
Looking only damage scorpions do, Stalker wins the damage race as soon there's more than one Stalker down (with the maximum number of Scorpion hits per round being actually 4 due to Epinephrine), and the damage difference gap is getting larger with every turn played due to poison mechanic.
BUT, you dont expect Dunes to be fast anyway, so thats not a big deal to me. Bigger issue I see is that deck is not as fluent with Dunes, mostly because of the way they clash with Precogs. IE, for scorpio to work, you need to have 2 cards in hand: buff and scorpio. If you only have one of those, using Precog with Stalkers can get you that second card which you will play that turn. Using Precogs with Dune will likely make you wait for another turn due to quanta you just spend. So there's no real gain in speed. Of course this is the issue only in early game.
That mark quanta usage is the biggest difference between two decks. Bad draws (ie, no Novas) with
mark will let you play and fly your Arsenics, building your poison counter faster, or let you drop unbuffed Stalker down after 2 turns, to help clear your hand. Same draws with
mark wont give you any possible damage output, and you'll need to wait one more turn to drop first unbuffed Dune.
Now, this text can look like Dunes suck or that I dont like the deck, but really, its just nitpicking of how decks preform in very specific situations. I lost only twice with them while testing it against T50, so the deck definitely works. Also, having the opponent poison himself to death is all kinds of awesome.
I prefer the Stalker version, but Dune version is definitely fun, and I would look into how to improve the flow of the game with average to bad draws.