Registered to post, I'll give as much info as I can. I checked the known bugs, this does not appear to be the same issue, but it may be related.
AI plays Vampire, enters play correctly as 4/3. AI later plays Nightfall, Vampire is now 5/4 (still correct). AI plays Eclipse, Vampire now 6/4 (still correct).
Here's where it starts to go awry.
I put a Pulverizer into play and eliminate the Eclipse. Vampire still shows as 6/4 (incorrect) - the two Nightfalls are still in play. On subsequent turns, I eliminate one Nightfall per turn. With the elimination of the second and last Nightfall, the Vampire becomes 5/3.
Hope that helps - I likely won't be back to check replies.