I actually did this a while ago, but somehow forgot to post my results, so here we go, better late than never!
My deck of choice was "turin's ludicrous speed deck", as I believe it's called, which is basically just the upgraded version of the mono-Shrieker deck. (List: 16 Stone Tower, 6 E-Graboids, 6 E-Shrieker, 1 Long Sword, 1 E-Antlion)
Stats after 90 minutes:
76 wins
1 loss
+ 1433 coins (counting money won from spins, but not from selling cards)
+ 1334 score.
As you can see, the deck is so fast, it almost wins a game per minute. I think I overall spent more time spinning and clicking to my next match than actually playing.
So the deck is a great choice if you're grinding for score (probably the best in the game) and aren't a big fan of losing. The latter is something the deck doesn't really do, as my one loss came from getting a zero-pillar hand while my opponent had the solid triple-Devourer start. After that I had to play like another 200 games before losing the next one.
On the flipside the deck is pretty monotonously to play, so if you want to do something that makes you feel smart, maybe you should go back to farming AI5/FGs.