I've been testing it with antimatter added. So far, no noticeable result changes. It can help get control of the board if you draw it early though, since it's essentially killing the creature. One less dragon or such for you to devour.
And you could also add a PA (especially after v1.17), but I don't see the point of flying weapon. Unless you desperately need to rewind a plagued creature or a huge growth creature (which you should just mutate anyway), you just don't play the eternity until you have a single card left in your deck. And by then, you've usually had the pulvy up long enough to destroy what you need. In addition, there's always the possibility of a destroy or steal mutant.