Fractal seems somewhat pointless without FFQ.
Fractal is the single most important card in the deck simply because of how many different ways it can be used.
1) Fractal allows you to set up your final turn perfectly for easy EM's. That's because your weapon damage occurs after any first-row Perm healing.
2) Fractal is great to use on critters in elements you don't have much use for, namely
etc. I've pulled off several 8 turn wins against Ferox using an early Fractal on a Frog for example.
3) Fractal lets you get useful CC type critters to use against FGs, like Oty Ulitharid Maxwell's
Just a quick example of how I like to use my Fractal against each FG:
Akebono: Usually never get around to using it, but if I can I use it as soon as possible on a Destroyer to get damage out faster. Often times it takes too long to get 11
needed to get out the nymph + UG so I don't even bother planning for it.
Chaos Lord: If I can't get a Pulvy out protected I like to Fractal the Werewolves. They do wonders at helping to tear down Diss Field and as a fun bonus the AI loves to use Improve on 6|6 Werewolves often giving me some very useful critters.
Dark Matter: If the AI plays out a nymph I'll save a Quint and Fractal an Oty to devour his field with. It's quite fun.
Destiny: Who cares, you don't even need to Fractal to win this one. Occasionally I'll Fractal a Maxwell's if there are some good targets for me to go after.
Divine Glory: Fractal a Destroyer, assuming I live long enough to even worry about it.
Dream Catcher: Ideally I like to Fractal the Physalia but with all the BH's and QS's and the BE spam on pillars I generally find myself using it on Micro Aboms since that's all I have quanta to play out.
Elidnis: Save a Quint, Fractal an Ulitharid. Piece of cake.
Eternal Phoenix: Fractal on his MPs to draw out CC and give me a repeatable source of damage.
Ferox: Fractal on the Frogs is very effective. Late game using it on the Dragons is fun too.
Fire Queen: Pretty much use it on anything you want.
Gemini: UG is great here so I usually don't bother using it except to set up for the EM.
Graviton: Does it really matter? HP too high for Otys and Firemasters gets RoF'd and eaten. Generally just use it for a final burst.
Hecate: PA your Permafrost and then Fractal the Voodoo Dolls with the Eclipse out. Makes for lots of fun and free damage when you pop UGs
Hermes: Can you Fractal PA Dim Shields? No? Good luck surviving long enough for it to matter then.
Incarnate: Fractal Vampires is fun for tearing down Bone Walls. Same with Elite Skeletons.
Jezebel: Destroyers usually. Depends alot on what she has on the field.
Lionheart: Usually Fractal for a final burst simply because unless you can deny
grabbing Scarabs or Pharaohs is pointless.
Miracle: Fractal a Pegasus and then wait and use their Dive for a huge final burst.
Morte: Fractal a Condor then pop all your UGs and finish him off with 8 20+ attack condors for the OTK.
Neptune: Generally I find hitting the Abyss Crawlers to be the best choice.
Obliterator: Fractal for the final EM burst on whatever.
Octane: Doesn't matter much once you PA a Pulvy isn't pretty much an autowin.
Osiris: Hit a Scarab early if you can, otherwise save it up for the final push.
Paradox: Usually save it for late game Destroyer Fractal
Rainbow: Auto-quit. Really is no Fractal use I've found that's helpful against the mass PC spamming.
Scorpio: Save a Quint and Fractal an Ulitharid. Coupled with the Purify in the deck and the Permafrost you can effectively lock down his ability to rack up fast poison.
Seism: Depends on your quanta. I like to hit Steel Golems if I can but I've used it on Gemfinders before just to keep the
rolling in for Destroyer growth.
Serket: It's fun to Fractal his Deathstalkers and troll him back.