From the thread on Decay:
The key vs. Paradox is waiting for him to slap at least two Blessings on one or two creatures before you Antimatter them. Spam the rest, it doesn't matter. Then, when he gets close to dying, pay careful attention to his life totals to make sure he doesn't Miracle.
This often requires spending 2 of your Nymph's Tears on HIS Aether Towers to create Aether Nymphs, and then hitting them with Antimatter and Liquid Shadow on the same turn they're created.
That trick -- using Tears on an opponent's Tower and then Anti/LSing it right away -- is useful vs. Miracle as well. I've also used them to give Destiny a pair of Precog Nymphs and then let her draw herself out with them.