The differences between our statistics are exactly what I was referring to in my USEM versus USEMosis discussion.
(I felt like I should quote something, but not the whole text)
I am assuming you mean this statement:
"Even though I managed to provide stats which support the fact that USEMosis makes more score/electrum per hour over the original USEM, I would still suggest using the older variation unless you are extremely experienced with AI3 grinding."
Not really sure I need to defend my experience here, but my ~3000ish games of USEM and ~1000ish games of USEMosis definitely pale in comparison the the number you have played. On the other hand, I am closing in on 400k score and have only played since mid-December, most of this of which has come from AI3 farming as well.
I feel like the actual strategy behind playing USEMosis requires no actual thought in developing after a couple hundred games. From that point forward, it is all instinctive (meaning you shouldn't encounter anything that actually slows you down to think through).
While you certainly are the USEM master, I don't think the difference in speed for USEM can be explained by experience or play style, where the deck play itself is mainly point and click. If we are truly playing with the same CPU capacity, I would say the difference would be that you are faster at maneuvering a mouse than me? While I don't claim to be the most adept clicker in the world, I doubt I fail to the point of a 2 second difference per game. I always get the mouse in place and ready to go before my turn hits. To me, there is obviously something else at play, which I believe still has to do mostly with a hardware difference. (my laptop is 4 years old?)
In reference to our difference in USEMosis stats, as stated before, this is my 4th time I've run the comparison and USEMosis has performed quite differently on each occasion. Once, I got the most rediculously efficient stats (sub 7.0 TTW, 83% EM), another time it underperformed USEM. I chose to post the latest one I did because I felt it was a good representation of the most common performance. Naturally, the makeup of USEMosis leads to much more variation in games. There are bad times you are stuck with two mitosis and no creatures, mitosis with not enough quanta to play/activate it, or there are glorious times you start with a bunch of quanta, a creature, and a mitosis to go crazy with while not hitting CC.
All in all, the difference between our posted stats is only a matter of a couple of seconds. The main point is that I wanted to reaffirm your original assertion that USEMosis is more efficient than USEM, supported by in-depth stats.