Wow, this is great against decks with vampires or minor vampires as they drain HP after they're hit with antimatter. Very nice since it lowers the amount of firebolts or fire quanta needed. Generally I get my shields stolen in the same match ups that have the AI dropping vampires so it balances out some.
I've had issues with weapons like pulverizer and titan, either losing pillars or just damage that I can't antimatter. Also a few times I've run out of cards before I had enough quanta, due to earkquakes.
So to handle those issues I added 2 more pillars and 2 deflagrations, and took out 1 antimatter. The deflags can be handy against catapults too.