I don't really like to use the trainer. It's probably just me being silly but, for me, part of the fun of the game is trying out different ideas. If I'm going to try out everything in a little bubble where I'm insulated from any harm that might befall me, then what's the point in playing the main game at all, anyway? If I'm only going to play decks that are completely optimised, then why bother playing any decks other than those which are proven to be the best against whatever league I'm looking to play against?
To be honest, as far as what I get out of the game goes, if I was going to start doing that, then I might as well just only play in trainer.