After a Trials match the other day, Zawadx and I were discussing the effectiveness of 6-weapon 24-tower mono decks.
It was clear right away that Fahrenheit took first place - its damage ramp is far too strong for any other weapon to come close in terms of a race from 100 to 0.
As a bit of a thought experiment, I ran some stats on animated weapon decks, using a 6-weapon 6-Animate Weapon 18-tower format.
This environment is obviously biased against certain elements, whose weapons' primary function is for control instead of damage, such as Electrocutor, Pulverizer and especially Poseidon. On the other hand, certain weapons are given advantages in this situation, such as Eagle's Eye due to the way the AI uses the Animate Weapon card, and to Eternity for the environment of the simulation itself. Despite these points, the simulations have produced some interesting results.
Please note that this data was collected just for fun, and is in no way meant to implicate superiority of any one weapon over another. Just an interesting read if you're into this kind of thing. All data was produced by simulating 1000 games per matchup for each deck. Matchups with winrates between 45-55% are counted as draws.