Druid's Staff comes it at number one, just because it's so much fun gaining 60+ life a turn once you have a few Animated Adrenalined Quitessenced Druid Staves out. Just don't choose it for your quest weapon, because it's easy to farm via AI3.
Then comes Pulverizer, and Eternity. They're just too useful in a variety of rainbow decks.
Follow that up with Eagle's Eye (also easy to farm) and Lobotomizer. Repeatable creature control = the win!
Then comes Titan, Morning Glory, then Arsenic and Fahrenheit. Hard-to-stop damage and ever-increasing damage are good.
Second-to-last, we have Poseidon -- an excellent tool under very specific circumstances, but those circumstances are hard to find -- and so is a Poseidon!
Finally, we round off with Discord and Vampire Stiletto -- one of which is annoying, but not lethal; the other is measurably inferior to Druid Staff in every respect and needs a boost. They basically suck. Though I understand that Discord may be changing to eat quanta instead of scrambling it -- that would immediately bump it way up in the rankings.