You can get advantage from it if you have only high HP creatures, immortals, borrowed creatures or no creatures at all.
As you can see in the example deck I posted on OP. That deck has no creature in it.
Thanks for the hints, was more or less what I meant regarding no creatures.
Not sure if high HP is really a guarantee that pandemonium will be of advantage, I guess depends on the specific situation, but immortals sounds like a good idea to combine it with pandemonium, maybe I'll try it.