^ Fire Queen may play 2 or more Elite Firefly Queens in a single turn. Lobotmizing both of them in the same turn prevents Elite Fireflies spamming, which allows Fire Queen to play
cards, like Fire Lance and Fahrenheit.
Morte or Incarnate may play 2 or more Retroviruses in a single turn. Lobotomizing all of them is vital, you will certainly lose otherwise.
Elidnis may spam 2 or more Ulitharids and Pupper Fish in a single turn. Lobotomizing any of these creatures is helpful, since Ulitharids love removing RoL's bioluminessence skill and Pupper Fishes poison you.
Osiris may play lot of Pharaohs in a single turn. Their Scarabs are deadly to RoLs, so removing their skill as fast as possible is vital.
For me, a 8|7 Crusader with 1
:Lobotomise is better than both Archangels and Light Dragons, even if I need two turns to achieve this. Also, there is no useless weapon to endow. Eagle's Eye makes Crusade a 10|7 creature, I don't give a damn if it can't use its Sniper ability. Vampire Dagger gmakes him 9|7 and gives Vampire, Discord 9|7 and Scramble, Jade Staff 7|7 and Regenerate, Arsenic 7|7 and Poisonous, Pulveriser 8|7, Fahrenheit 8|7, Titan 10|7 and gives Momentum, Eternity 7|7, Poseidon 7|7 and Electrocutor 8|7 with Lobotomise ability. At worst, Crusader will become a vanilla non-airborne version of Archangel. At best, it will completely dominate the battlefield... 8)