The thing I find about Life is that it's creatures are very very frail... but Mitosis is an amazing card and so is Adrenaline. By splashing in Aether, it gives you access to Quintessence which can protect a Mitosis "mother" card. If you put in Dark, you can grab the Cloak card and Darkness has Steal for Permanent Control, but in my experience Drain Life's damage is too low to use as a "nuke" card (only 2 damage if less than 10 Darkness quantum.)
For some reason, I really enjoyed running a Fire/Life rush. Both of them are about rushing fast and Fire Bolts, Deflagrations, and Rain of Fire are surprisingly versatile. On the downside, you're pulling less Life cards.
Anyway, choice is up to you. Offhand, Time is a good element but often focuses on speeding up card draw with Golden Hourglasses or using Rewind as delay-tactic Creature Control (in the same vein as Iridium, Freeze, or Basilisk Blood) which only mitigates damage, but doesn't prevent it ultimately. Life has a good shield in Thorn Carapace, but the cost is a bit prohibitive... if you like using Time, why not use a Procrastination shield or two?