I love the mechanics of this card, and it's very well balanced. Otyughs could eat poisonous creatures with this? Also interesting that unupped is a spell, but upped is a permanent. I guess SoG is like that, but unupped shard does nothing.
The name of the upped version doesn't seem to fit though. Antibiotics kill biotic things, such as bacteria. Poison isn't caused by bacteria, but by toxic chemicals. It's different from disease. But I guess viruses aren't affected by antibiotics, nor are they poisonous, yet they still cause poison. So it's not a big deal.