Pity, I kind of liked the centered look.
I made the Empath the upgraded one since I like being optimistic and didn't want the bad guy as the upgraded version, but I can see your point. I could switch the two.
I had thought to have both abilities usable multiple times. The Empath would only have maybe 2-3 uses out of it max if you use it by itself and have several creatures out in the field. If you pair it with a Guardian Angel or use Plate Armor, however, you could extend the life of the Empath and keep feeding health to your other creatures. Though solo use wouldn't be bad either, in a pinch it will keep some of your Fireflys from death by a Rain of Fire.
As for the False Prophet, I thought multiple ability use would be better. Sure some combination of Aflatoxin/Graveyard/Bone Wall would rock with this card, but those are all fairly pricey cards. If you can get them all out into the field without interruption and without dying first, then why not? Fractal/Devourer is similarly deadly if you can pull it off in time. Besides, all of your Malignant Cells would die the first time you use the ability, so they wont replenish. If you get skeletons off of them, they will be dead another two turns after that. The field is then presumably empty other than an absolutely huge False Prophet. This assumes the False Prophet was not interrupted along the way (by freeze, rewind, fire bolt, etc.) One solution though could be that each use of the False Prophets ability cause +0/-2 to each other creature instead of +0/-1. That would reduce the number of buffs it gets off of friendly creatures.