No, you cannot touch a players hand. It is his sacred place. This card is way to OP. How do you destroy a spell? Spells are a one time use... If you want this idea to go through you could go with...
For every permanent / creature you have destroy one of your opponents permanent / creature along with yours.
Unupped destroys all the permanent / creatures on your side no matter what, upped destroys only enough to destroy your opponents.