My stuff:
Mark = Air
Permanents = Golden hourglass, mindgate, reflective shield
Enemy AI's stuff:
Mark = Air
Permanents = Empathic bond, Hope, Owl's eye
Creatures = Firefly queen, fireflies
1) I put antimatter on a firefly queen
2) I put Adrenaline on same firefly queen (attack value still reads as -3 at this point)
3) firefly queen attacks me multiple times and hurts me each time instead of healing me (verified my hp goes down from each attack)
Note that I observed the firefly queen healing me each attack before I put adrenaline on her