That's an... interesting idea :p I'm fairly skeptical as to whether it would actually work, though. I'd think a death mark and a few pends would be way easier than all those SoRs, since physalias aren't exactly quanta intensive.
The deck I want to build, but have never tried yet, is fractal physalia SoP/flooding. I wouldn't even use the physalias for poison, I'd just flood the board and make a dozen dragon-sized clams out of them! :p Just a thought... I'd love to see how someone did with that.