First I want to thank everybody for replying.
... but with my luck, I'll never draw any from the 4 sources, ...
In the newest version there are 5. Plus you don't need to use liquid shadow in the first 4-5 turns, it is ok to wait a bit for that.
If you're going to use the Mutation as a pseudo-Lobotomizer, why not trade it for a Liquid Shadow?
Could be an option, but there are reasons not to. Mutation is not used only as a pseudo lobo but also to buff a small creature. Another very important reason (especially with my version) is that it uses entropy qanta instead of darkness (I think it is good to have a chance to lobo with either color).