Okay, I have a few observations on this card.
I started a newbie using Darkness, which has Aether as the second element. I bought Fractal in the bazaar very early, and it's been a huge help.
Opponent is playing a water/death poison-spam deck? Fractal my one minor vampire and out-heal the poison long enough to win.
Opponent is beating me soundly by normal means? Let my devourers and obsidian pillars build up dark quanta, then Fractal my black dragon and lay down 7 of the reptiles in a single turn.
Dragon's already died when Fractal becomes useable? Use it on one of the devourers and then drain life a few turns later.
I've considered using Fractal on an opponent's virus a few times, but decided it wasn't worth it. Not compared to the flock of black dragons powered by devourers tactic.