In an Entropy mark Rainbow, which runs 6 Supernovas, it is possible to get enough quanta on turn 3. The big drawback to Entropy mark is that you don't have as much
to run hourglasses/prevent deckout consistently with Eternity. If you know this combo is in your deck, you can draw extra cards pretty freely until you're down to ~10 (at which point you should slow down and make sure you'll be able to play your Eternity) cards remaining. That means even if you only pack one EE or Basilisk Blood there's a decent chance you can get this going. If not, run a few of these cards and your problem is solved.
There's also the matter of Supernova not generating any excess
(costs 2, generates 2), where this card would net you a minimum of 4
by the time its destroyed.